Abstract:
The effect of sedatives and analgesics on heart rate, respiration rate and rectal temperature
were observed. Heart rate and respiration rate significantly (p<0.01) decreased during
sedation with xylazine hydrochloride plus 2% lignocaine hydrochloride or 0.5% bupivacaine
hydrochloride. A significantly decreased (p<0.01) heart rate and respiration rate also found
during sedation with diazepam plus 2% lignocaine hydrochloride or 0.5%bupivacaine
hydrochloride. Two percent lignocaine hydrochloride showed short onset, rapid spreading
and no side effect. Duration of analgesia was longer with 0.5 % bupivacaine hydrochloride
(55.88±1.58 min in Group B and 48±11.25 min in Group D) compared to 2% lignocaine
hydrochloride (39.60±5.77 min in Group A and 43.6±5.81 min in Group C). Xylazine
hydrochloride showed short onset and long duration of sedation compared to diazepam.
Therefore, herniorraphy, xylazine hydrochloride can be used as a better sedative while 0.5 %
bupivacaine hydrochloride can be used as a local analgesic for longer duration of action.
